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Article

Drug Target Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Atrial Fibrillation.

Cardiology - 1 Jan 2024

Li Fuyuan, Mei Yibin, Wu Qiongbi, Wu Xianjun

Abstract excerpt

INTRODUCTION: Atrial fibrillation (AF) is a prevalent cardiac arrhythmia with significant clinical implications. The potential influence of lipid-lowering therapies, specifically PCSK9 inhibitors (PCSK9i) and HMG-CoA reductase inhibitors (statins), on AF risk remains a topic of interest. This mendelian randomization (MR) study aimed to elucidate the causal relationship between genetically predicted inhibition of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

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Share to Polymorphism, Single Nucleotide

Share to Proprotein Convertase 9

Source

Open in PubMed Open full text

Identifiers

PMID: 38531334
DOI: 10.1159/000538551
PMCID: PMC11449189

Genes

PCSK9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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