Article

Within-host evolution of SARS-CoV-2: how often are <i>de novo</i> mutations transmitted?

2023-08-08

Abstract excerpt

Despite a relatively low mutation rate, the large number of SARS-CoV-2 infections has allowed for substantial genetic change, leading to a multitude of emerging variants. Using a recently determined mutation rate (per site replication), as well as parameter estimates for within-host SARS-CoV-2 infection, we apply a stochastic transmission-bottleneck model to describe the survival probability of de novo SARS-CoV-2...

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Literature Corpus work: 5e1b673e-0c2b-5dd4-82ad-5e912530c2cf
DOI: 10.1101/2023.08.08.552503

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