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Article

Controlling long-term SARS-CoV-2 infections can slow viral evolution and reduce the risk of treatment failure.

Scientific reports - 19 Nov 2021

Van Egeren Debra, Novokhodko Alexander, Stoddard Madison, Tran Uyen, Zetter Bruce, Rogers Michael S, Joseph-McCarthy Diane, Chakravarty Arijit

Abstract excerpt

The rapid emergence and expansion of novel SARS-CoV-2 variants threatens our ability to achieve herd immunity for COVID-19. These novel SARS-CoV-2 variants often harbor multiple point mutations, conferring one or more evolutionarily advantageous traits, such as increased transmissibility, immune evasion and longer infection duration. In a number of cases, variant emergence has been linked to long-term infections...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34799659
DOI: 10.1038/s41598-021-02148-8
PMCID: PMC8604936

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