Article

Intra-Host Mutation Rate of Acute SARS-CoV-2 Infection During the Initial Pandemic Wave

2023-03-25

Abstract excerpt

<h4>Background</h4> Our understanding of SARS-CoV-2 evolution and mutation rate is limited. The rate of SARS-CoV-2 evolution is minimized through a proofreading function encoded by NSP-14 and may be affected by patient comorbidity. Current understanding of SARS-CoV-2 mutational rate is through population based analysis while intra-host mutation rate remains poorly studied. <h4>Methods</h4> Viral genome analysi...

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Literature Corpus work: 7bbf3bcb-13a1-5252-a45f-13e0c2cff913
DOI: 10.1101/2023.03.24.534062

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