Article

Nuclear SUN2 coordinates endothelial cell-matrix interactions to regulate blood vessel homeostasis and barrier function

2026-05-20

Abstract excerpt

<h4>ABSTRACT</h4> Vascular endothelial cells respond to environmental forces to remodel vessels during development and to achieve homeostasis, and mis-regulated responses lead to vascular dysfunction and disease. The nucleus participates in force transduction to cell-matrix junctions via the Linker of Nucleoskeleton and Cytoskeleton (LINC) complex that resides in the nuclear envelope, but how these forces are reg...

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Literature Corpus work: 5e0f4b9f-f570-5d45-844d-822e3aa84120
DOI: 10.64898/2026.05.18.725979

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