Article

The VE-cadherin/AmotL2 mechanosensory pathway suppresses aortic inflammation and the formation of abdominal aortic aneurysms

2021-06-15

Abstract excerpt

Arterial endothelial cells (ECs) have the ability to respond to mechanical forces exerted by fluid shear stress. This response is of importance, as it is protective against vascular diseases such as atherosclerosis and aortic aneurysms. Mechanical forces are transmitted at the sites of adhesion to the basal membrane as well as cell-cell junctions where protein complexes connect to the cellular cytoskeleton to rela...

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Literature Corpus work: 0dcd3bb4-6db0-5853-9c06-e4d6e55d334c
DOI: 10.21203/rs.3.rs-600069/v1

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