Article
The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing.
Nucleus (Austin, Tex.) - 1 Mar 2012
Rashmi R N, Eckes Beate, Glöckner Gernot, Groth Marco, Neumann Sascha, Gloy Joachim, Sellin Lorenz, Walz Gerd, Schneider Maria, Karakesisoglou Iakowos, Eichinger Ludwig, Noegel Angelika A
Abstract excerpt
Nesprin-2, a type II transmembrane protein of the nuclear envelope, is a component of the LINC complex that connects the nuclear lamina with the actin cytoskeleton. To elucidate its physiological role we studied wound healing in Nesprin-2 Giant deficient mice and found that a loss of the protein...
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