Article

Alternative Splicing And Global Transcriptome Changes Associated With LPS Stimulation In Human Peripheral Blood Mononuclear Cells

2025-11-10

Abstract excerpt

<h4>Introduction</h4> Lipopolysaccharide (LPS), a major component of gram-negative bacterial cell walls, elicits strong innate immune activation and is a widely used model for studying inflammatory responses. While the transcriptional response to LPS stimulation has been characterized, the role of alternative splicing (AS) in modulating this response remains largely unexplored. <h4>Methods</h4> Using deep RNA se...

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Literature Corpus work: 8dce30e5-a154-531c-bd59-d9059e73f6a5
DOI: 10.1101/2025.11.09.687437

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