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Single-cell analyses identify tobacco smoke exposure-associated, dysfunctional CD16 <sup>+</sup> CD8 T cells with high cytolytic potential in peripheral blood

2019-09-27

Abstract excerpt

<h4>SUMMARY</h4> Tobacco smoke exposure has been found to impact immune response, leukocyte subtypes, DNA methylation, and gene expression in human whole blood. Analysis with single cell technologies will resolve smoking associated (sub)population compositions, gene expression differences, and identification of rare subtypes masked by bulk fraction data. To characterize smoking-related gene expression changes in...

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Literature Corpus work
5ddf7fbb-72d4-577c-8172-241fec419946
DOI
10.1101/783126
Open publication

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Single-cell analyses identify tobacco smoke exposure-associated, dysfunctional CD16 <sup>+</sup> CD8 T cells with high cytolytic potential in peripheral bloodDOI 10.1101/783126
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