Article

Sexual-dimorphism in human immune system aging

2019-09-08

Abstract excerpt

Differences in immune function and responses contribute to health- and life-span disparities between sexes. However, the role of sex in immune system aging is not well understood. Here, we characterize peripheral blood mononuclear cells from 172 healthy adults 22-93 years of age using ATAC-seq, RNA-seq, and flow-cytometry. These data reveal a shared epigenomic signature of aging including declining naïve T cell an...

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Literature Corpus work: cf5c6cf1-c890-52a7-a129-2aa22a958677
DOI: 10.1101/755702

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