Article
Conservation of antiviral systems across domains of life reveals novel immune mechanisms in humans
2022-12-12
Abstract excerpt
Viral infection is a common threat to prokaryotic and eukaryotic life, which has resulted in the evolution of a myriad of antiviral systems. Some of these eukaryotic systems are thought to have evolved from prokaryotic antiphage proteins, with which they may display sequence and structural homology. Here, we show that homologs of recently discovered antiphage systems are widespread in eukaryotes. We demonstrate th...
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Identifiers and source
- Literature Corpus work
- e2b05b94-e185-5023-b1d7-74d10fe161f0
- DOI
- 10.1101/2022.12.12.520048