Article

Polygenic Risk Associated with Alzheimer’s Disease and Other Traits Influences Genes Involved in T Cell Signaling and Activation

2023-05-13

Abstract excerpt

T cells, members of the adaptive immune system known for their ability to respond to an enormous variety of pathogens and other insults, are increasingly recognized as important mediators of pathology in neurodegeneration and other diseases. Previously, we and others have shown that T cell gene expression phenotypes are regulated by genetic variants associated with autoimmune disease, neurodegenerative disease, an...

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Literature Corpus work: 1161b0d9-7bd7-553e-bf6a-6f0e49a8e689
DOI: 10.1101/2023.05.10.540219

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