Article

Investigating the role of Vangl2 in the postnatal lung

2016-01-01

Abstract excerpt

The non-canonical planar cell polarity (PCP) pathway is important for embryonic development of many organs including the lungs. However, comparatively little is known about the role of this pathway in adults, partly because homozygous mutations of many PCP genes result in neonatal lethality, preventing post-natal investigations. We studied Looptail (Lp) mice, which carry a dominant negative mutation in Van Gogh-li...

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Literature Corpus work: 5d9ccc0d-4a53-5953-9c7d-6965373c06e6
DOI: 10.25560/51508

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