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Article

The PCP genes Celsr1 and Vangl2 are required for normal lung branching morphogenesis.

Human molecular genetics - 1 Jun 2010

Yates Laura L, Schnatwinkel Carsten, Murdoch Jennifer N, Bogani Debora, Formstone Caroline J, Townsend Stuart, Greenfield Andy, Niswander Lee A, Dean Charlotte H

Abstract excerpt

The lungs are generated by branching morphogenesis as a result of reciprocal signalling interactions between the epithelium and mesenchyme during development. Mutations that disrupt formation of either the correct number or shape of epithelial branches affect lung function. This, in turn, can lea...

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Source

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Identifiers

PMID: 20223754
DOI: 10.1093/hmg/ddq104
PMCID: PMC2865378

Genes

FGF10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20223754-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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