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Article

Gpr177 regulates pulmonary vasculature development

25 Jul 2013

Abstract excerpt

Establishment of the functional pulmonary vasculature requires intimate interaction between the epithelium and mesenchyme. Previous genetic studies have led to inconsistent conclusions about the contribution of epithelial Wnts to pulmonary vasculature development. This discrepancy is possibly due to the functional redundancy among different Wnts. Here, we use Shh-Cre to conditionally delete Gpr177 (the mouse...

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PMID: 23884445
DOI: 10.1242/dev.095471

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