Article

Transcription factor-based gene therapy to treat glioblastoma through direct neuronal conversion

2020-08-20

Abstract excerpt

Glioblastoma (GBM) is the most prevalent and aggressive adult primary cancer in the central nervous system (CNS). Therapeutic approaches for glioblastoma are under intense investigation, such as the emerging immunotherapy, but so far only marginal progress has been made due to the heterogeneity and highly invasive nature of glioblastoma. Here, we propose an alternative approach to tackle GBM through reprogramming...

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Literature Corpus work: 5d87ecf9-d116-547f-a3c2-6ddcde861d10
DOI: 10.1101/2020.08.19.257444

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