Article
Genetic relations between leukocyte counts, type 1 diabetes, and coronary artery disease
2024-04-01
Abstract excerpt
<h4>Hypothesis/Aim</h4> Type 1 diabetes (T1D) is associated with excess coronary artery disease (CAD) risk even when known cardiovascular risk factors are accounted for. Genetic perturbation of hematopoiesis that alters leukocyte production is a novel independent modifier of CAD risk. We examined whether there are shared genetic determinants and causal relationships between leukocyte counts, T1D, and CAD. <h4>Met...
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Identifiers and source
- Literature Corpus work
- 5d2cc7fa-7623-5967-b38b-24c8566b5e2a
- DOI
- 10.1101/2024.04.01.24305155
