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Unveiling the influence of circulating immune cells count on type 1 diabetes: Insight from bidirectional Mendelian randomization.

Medicine - 27 Sept 2024

Luo Jia, Wang Jing, Xiang Yukun, Wang Ningning, Zhao Xin, Liu GengYan, Liu Lihui, Chang Haoxiao

Abstract excerpt

Observational studies have demonstrated an association between circulating immune cell and type 1 diabetes (T1D) risk. However, it is unknown whether this relationship is causal. Herein, we adopted a 2-sample bidirectional Mendelian randomization study to figure out whether circulating immune cell profiles causally impact T1D liability. Summary statistical data were obtained from genome-wide association study...

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Basophils
Diabetes Mellitus, Type 1
Genetic Predisposition to Disease
Genome-Wide Association Study
Leukocyte Count

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lymphocyte Count

Mendelian Randomization Analysis

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Identifiers

PMID: 39331871
DOI: 10.1097/MD.0000000000039842
PMCID: PMC11441873

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