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Genome-wide association study on coronary artery disease in type 1 diabetes suggests beta-defensin 127 as a risk locus.

Cardiovascular research - 21 Jan 2021

Antikainen Anni A V, Sandholm Niina, Trégouët David-Alexandre, Charmet Romain, McKnight Amy Jayne, Ahluwalia Tarunveer S, Syreeni Anna, Valo Erkka, Forsblom Carol, Gordin Daniel, Harjutsalo Valma, Hadjadj Samy, Maxwell Alexander P, Rossing Peter, Groop Per-Henrik

Abstract excerpt

AIMS: Diabetes is a known risk factor for coronary artery disease (CAD). There is accumulating evidence that CAD pathogenesis differs for individuals with type 1 diabetes (T1D). However, the genetic background has not been extensively studied. We aimed to discover genetic loci increasing CAD susceptibility, especially in T1D, to examine the function of these discoveries and to study the role of the known risk...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32077919
DOI: 10.1093/cvr/cvaa045
PMCID: PMC8453280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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