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Adverse effects of gestational diabetes mellitus on fetal monocytes revealed by single-cell RNA sequencing

5 Dec 2023

Abstract excerpt

Gestational diabetes mellitus (GDM), the most prevalent metabolic disorder during pregnancy, has long-term risks of metabolic diseases in offspring. However, the underlying mechanisms remain unclear. Here, we analyzed single-cell transcriptional data of cord blood mononuclear cells (CBMCs) from fetuses of healthy and GDM mothers, peripheral blood mononuclear cells from children and adolescents, and coronary...

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PMID: 38188508
DOI: 10.1016/j.isci.2023.108637

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