Article

Quantifying the impact of Human Leukocyte Antigen on the human gut microbiome

2020-01-15

Abstract excerpt

<h4>Objective</h4> The gut microbiome is affected by a number of factors, including the innate and adaptive immune system. The major histocompatibility complex (MHC), or the human leukocyte antigen (HLA) in humans, performs an essential role in vertebrate immunity, and is very polymorphic in different populations. HLA determines the specificity of T lymphocyte and natural killer (NK) cell responses, including aga...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5ce945e9-994a-5f64-89f4-6a1fb28bac28
DOI: 10.1101/2020.01.14.907196

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Quantifying the impact of Human Leukocyte Antigen on the human gut microbiomeDOI 10.1101/2020.01.14.907196Read

Quantifying the Impact of Human Leukocyte Antigen on the Human Gut MicrobiotaSemantic proximity Read

HLA risk alleles and gut microbiome in ankylosing spondylitis and rheumatoid arthritis.Semantic proximity Read

The Influence of the Autoimmunity-Associated Ancestral HLA Haplotype AH8.1 on the Human Gut Microbiota: A Cross-Sectional Study.Semantic proximity Read

HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiomeSemantic proximity Read

<scp>HLA</scp> Alleles Associated With Risk of Ankylosing Spondylitis and Rheumatoid Arthritis Influence the Gut MicrobiomeSemantic proximity Read

Genetic risk for autoimmunity is associated with distinct changes in the human gut microbiome.Semantic proximity Read

Important denominator between autoimmune comorbidities: a review of class II HLA, autoimmune disease, and the gut.Semantic proximity Read

Host genetic variation impacts microbiome composition across human body sites.Semantic proximity Read

HLA-DQ2/8 genotype is associated with strain-level gut microbiome divergence and lower serum pantothenate in healthy adultsSemantic proximity Read

The HUNT study identifies host genetic factors reproducibly associated with human gut microbiota composition.Semantic proximity Read

HLA, gut microbiome and hepatic autoimmunity.Semantic proximity Read

The effect of immunogenetic variability on human health : bioinformatics investigations from different perspectivesSemantic proximity Read