Article

HLA alleles associated with risk of ankylosing spondylitis and rheumatoid arthritis influence the gut microbiome

2019-01-11

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Objectives</h4> HLA alleles affect susceptibility to more than 100 diseases, but the mechanisms to account for these genotype-disease associations are largely unknown. HLA-alleles strongly influence predisposition to ankylosing spondylitis (AS) and rheumatoid arthritis (RA). Both AS and RA patients have discrete intestinal and faecal microbiome signatures. Whether these changes are cause or...

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Literature Corpus work: a447a17a-a2fd-5a86-bd35-7481992f4644
DOI: 10.1101/517813

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