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Article

HLA risk alleles and gut microbiome in ankylosing spondylitis and rheumatoid arthritis.

Best practice & research. Clinical rheumatology - 1 Dec 2019

Xu Huji, Yin Jian

Abstract excerpt

Human leukocyte antigen (HLA) alleles are associated with a variety of autoimmune diseases. The composition of gut microbiome can be influenced by host immunity, which is partially regulated by HLA. In this review, first we provide evidence from animal and human studies on: if and how HLA-B27, HLA-DRB1 (shared epitope (SE)), and other HLA alleles alter the gut microbiome, then we analyzed the data for several...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to HLA-B27 Antigen

Share to HLA-DRB1 Chains

Share to Inflammatory Bowel Disease

Share to Spondylitis, Ankylosing

Source

Identifiers

PMID: 32279929
DOI: 10.1016/j.berh.2020.101499

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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