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Article

Limited efficacy and a concentration-dependent toxicity of MitoQ in porcine precision-cut kidney slices

2026-08-07

Abstract excerpt

<h4>Background: </h4> and Purpose: Ischemia–reperfusion injury (IRI) leads to excessive production of reactive oxygen species (ROS), primarily within the mitochondria. ROS generation is associated with poorer graft and patient outcomes following transplantation. Targeting mitochondrial ROS with ubiquinone (brand name MitoQ) is therefore of clinical interest. This research aimed to study the relation between MitoQ...

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Literature Corpus work
5cdb9840-455c-5960-897f-e8b7b74cef83
DOI
10.22541/authorea.15007189/v1
Open publication

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Limited efficacy and a concentration-dependent toxicity of MitoQ in porcine precision-cut kidney slicesDOI 10.22541/authorea.15007189/v1
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