Mitochondrial dysfunction during ischaemia reperfusion injury in models of organ transplantation

Abstract excerpt

Organ transplantation is the only treatment for patients with severe and irreversible organ damage. Although the efficacy of transplantation has progressed immensely in recent years, one of the most damaging factors occurring during this surgical procedure, ischaemia reperfusion injury (IRI), is still a major contributor causing poor outcome. Ischaemia arises due to the lack of blood supply, leaving the tissue wit...

Topics

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• Acute Kidney Injury Research
• Autophagy in Disease and Therapy
• Liver Disease and Transplantation
• Liver Disease Diagnosis and Treatment
• Metabolism and Genetic Disorders
• Mitochondrial Function and Pathology
• Organ Transplantation Techniques and Outcomes
• Transplantation: Methods and Outcomes

Identifiers and source

Literature Corpus work

0dd5d849-79f6-5e94-8709-9506a63239a7

DOI

10.17863/cam.59632