Back to search

Article

A comparative analysis of acellular versus red cell based subnormothermic machine perfusion in human kidney transplantation

2026-01-07

Abstract excerpt

Normothermic machine perfusion (NMP) typically uses red blood cell (RBC)-based perfusates, with associated challenges, including free haem-driven ferroptotic tubular injury. Acellular perfusates avoid these risks. Subnormothermic machine perfusion (SMP, 32°C) may reduce metabolic demands while preserving organ viability, but the effect of perfusate type under these conditions remains unclear. In a paired experimen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
91e7853b-da02-55ff-ab7f-6b2882b5887a
DOI
10.64898/2026.01.06.697890
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
A comparative analysis of acellular versus red cell based subnormothermic machine perfusion in human kidney transplantationDOI 10.64898/2026.01.06.697890
Investigation of the transcriptional profile of human kidneys during machine perfusion reveals potential benefits of haemoadsorptionSemantic proximity
Transcriptomic profiling during normothermic machine perfusion of human kidneys reveals a pro-inflammatory cellular landscape and gene expression signature associated with prolonged delayed graft function after transplantationSemantic proximity
End of preservation normothermic machine perfusion of porcine kidneys after ischaemic injury reprograms metabolism and induces fibrosis after transplant despite unchanged function: insights from the renal proteomeSemantic proximity
Normothermic human kidney preservation drives iron accumulation and ferroptosisSemantic proximity
Identification of ferroptosis-associated genes exhibited in human kidney biopsies after one hour of normothermic machine perfusionSemantic proximity
Transcriptomic signatures during normothermic liver machine perfusion correspond with graft quality and predict the early graft functionSemantic proximity
Spatiotemporal transcriptomic analysis during cold ischemic injury to the murine kidney reveals compartment-specific changesSemantic proximity
Comparative analysis of kidney transplantation modeled using precision-cut kidney slices and kidney transplantation in pigsSemantic proximity
Chronic renoprotective effect of pulsatile perfusion machine RM3 and IGL-1 solution in a preclinical kidney transplantation model.Semantic proximity
PHENOTYPING REPAIR AFTER ACUTE KIDNEY INJURY: PRECISION MEDICINE TO CLINICAL TRIALS.Semantic proximity
Limited efficacy and a concentration-dependent toxicity of MitoQ in porcine precision-cut kidney slicesSemantic proximity
Orthobiologic-mediated Tissue Regeneration in Chronic Kidney Disease—Phase I Clinical Trial Prospectus and Study ProtocolSemantic proximity
Select a neighboring publication to make it the new centre.