Article

Effects of ketamine and propofol on muscarinic plateau potentials in rat neocortical pyramidal cells

2024-02-16

Abstract excerpt

Propofol and ketamine are widely used general anaesthetics, but have different effects on consciousness: propofol gives a deeply unconscious state, with little or no dream reports, whereas vivid dreams are often reported after ketamine anaesthesia. Ketamine is an N-methyl-D-aspartate (NMDA) receptor antagonist, while propofol is a gamma-aminobutyric-acid (GABAA) agonist, but these mechanisms do not fully explain h...

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Literature Corpus work: 5cd2e97d-13c2-5213-953b-0093a417cc18
DOI: 10.1101/2024.02.14.579884

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