Article
Propofol Regulates Arousal by Enhancing Inhibitory Synaptic Transmission of Noradrenergic Neurons in the Locus Coeruleus of Adult Male Mice
2025-06-09
Abstract excerpt
<title>Abstract</title> <p> Locus coeruleus-noradrenergic (LC-NA) neurons have been implicated to be involved in the effects of general anesthetics. However, the contribution of LC-NA neurons during propofol anesthesia remains unknown. We aimed to elucidate the mechanism of action of propofol in the LC-NA neurons. LC-NA neurons from adult male mice were identified by targeted expression of fluorescent proteins....
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Identifiers and source
- Literature Corpus work
- d4aa2daf-5d6e-54eb-9442-6bc05b89aa2a
- DOI
- 10.21203/rs.3.rs-6585147/v1
