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Propofol Regulates Arousal by Enhancing Inhibitory Synaptic Transmission of Noradrenergic Neurons in the Locus Coeruleus of Adult Male Mice

2025-06-09

Abstract excerpt

<title>Abstract</title> <p> Locus coeruleus-noradrenergic (LC-NA) neurons have been implicated to be involved in the effects of general anesthetics. However, the contribution of LC-NA neurons during propofol anesthesia remains unknown. We aimed to elucidate the mechanism of action of propofol in the LC-NA neurons. LC-NA neurons from adult male mice were identified by targeted expression of fluorescent proteins....

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Literature Corpus work
d4aa2daf-5d6e-54eb-9442-6bc05b89aa2a
DOI
10.21203/rs.3.rs-6585147/v1
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Propofol Regulates Arousal by Enhancing Inhibitory Synaptic Transmission of Noradrenergic Neurons in the Locus Coeruleus of Adult Male MiceDOI 10.21203/rs.3.rs-6585147/v1
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