Article

A network model of the modulation of gamma oscillations by NMDA receptors in cerebral cortex

2021-12-23

Abstract excerpt

Psychotic drugs such as ketamine induce symptoms close to schizophrenia, and stimulate the production of gamma oscillations, as also seen in patients, but the underlying mechanisms are still unclear. Here, we have used computational models of cortical networks generating gamma oscillations, and have integrated the action of drugs such as ketamine to partially block n-methyl-d-Aspartate (NMDA) receptors. The model...

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Literature Corpus work: f1b91c56-28e1-5959-a076-c615127e797e
DOI: 10.1101/2021.12.21.473671

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