Article

Sleep-related thalamocortical spindles and delta oscillations are reduced during a ketamine-induced psychosis-relevant transition state

2019-11-08

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> In schizophrenia, sleep spindles are reduced, supporting the hypothesis that the thalamus and glutamate receptors play a crucial etio-pathophysiological role, whose underlying mechanisms remain unknown. We hypothesized that a reduced function of NMDA receptors is involved in the psychosis-related spindle deficit. <h4>Methods</h4> An electrophysiological multisite cell-to-ne...

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Literature Corpus work: 08e35cde-58b1-5f7e-83fe-310d7d9e5a8d
DOI: 10.1101/833459

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