Article

The Effects of The General Anesthetic Sevoflurane on Neurotransmission: An Experimental and Computational Study

2020-11-24

Abstract excerpt

The brain functions can be reversibly modulated by the action of general anesthetics. Despite a wide number of pharmacological studies an extensive analysis of the cellular determinants of anesthesia at the microcircuits level is still missing. Here, by combining patchclamp recordings and mathematical modeling, we examined the impact of sevoflurane, a general anesthetic widely employed in the clinical practice, on...

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Literature Corpus work: 4b20828d-455b-53eb-98ef-8c748c10100e
DOI: 10.21203/rs.3.rs-109289/v1

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