Article

MMP-9 Reinforces Radiation-Induced Delayed Invasion and Metastasis of Surviving Neuroblastoma Cells Through Second-Signaling Positive Feedback With NFkB Via Both ERK and IKK Activation

2021-03-22

Abstract excerpt

<title>Abstract</title> <p>Neuroblastoma (NB) progression is branded with hematogenous metastasis and frequent relapses. Despite intensive multimodal clinical therapy, outcomes for patients with progressive disease remain poor, with negligible long-term survival. Therefore, understanding the acquired molecular rearrangements in surviving cells with therapy pressure and developing improved therapeutic strategies i...

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Literature Corpus work: 00ba4ea7-4722-5a94-b836-e38ca6df32ff
DOI: 10.21203/rs.3.rs-311771/v1

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