Article

Estimation of crossbridge-state during cardiomyocyte beating using second harmonic generation

2022-10-14

Abstract excerpt

Estimation of dynamic change of crossbridge formation in living cardiomyocytes is expected to provide crucial information for elucidating cardiomyopathy mechanisms, efficacy of an intervention, and other parameters. Here, we developed an assay system to dynamically measure second harmonic generation (SHG) polarization in pulsating cardiomyocyte and proved that the SHG anisotropy derived from myosin filaments in di...

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Literature Corpus work: 5c6c252c-3b06-561a-882b-a519c465a236
DOI: 10.1101/2022.10.13.512034

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