Article

Human cardiac tissues produce lower contractile stress and exhibit slower cross-bridge cycling in type 2 diabetes

2025-01-29

Abstract excerpt

<title>Abstract</title> <p>Background: Diabetes mellitus elevates the risk of developing heart failure and increases associated mortality rates. While the clinical features of diabetic cardiomyopathy have been extensively studied, the effects of diabetes and associated changes in metabolic state on contractile cross-bridge function are less well-understood. Using our suite of experimental methods designed to meas...

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Literature Corpus work: a56827f2-040d-5fee-82ef-8dbe0c25a0dc
DOI: 10.21203/rs.3.rs-5830942/v1

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