Article
Quantitative Evaluation of the Sarcomere Network of Human hiPSC-Derived Cardiomyocytes Using Single-Molecule Localization Microscopy.
International journal of molecular sciences - 17 Apr 2020
Lemcke Heiko, Skorska Anna, Lang Cajetan Immanuel, Johann Lisa, David Robert
Abstract excerpt
The maturation of iPSC-derived cardiomyocytes is still a critical point for their application in cardiovascular research as well as for their clinical use. Although multiple differentiation protocols have been established, researchers failed to generate fully mature cardiomyocytes in vitro possessing identical phenotype-related and functional properties as their native adult counterparts. Besides...
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