Article
From chaos to split‐ups – SHG microscopy reveals a specific remodelling mechanism in ageing dystrophic muscle
6 Nov 2012
Abstract excerpt
Duchenne muscular dystrophy (DMD) is a common inherited muscle disease showing chronic inflammation and progressive muscle weakness. Absent dystrophin renders sarcolemma more Ca(2+) -permeable, disturbs signalling and triggers inflammation. Sustained degeneration/regeneration cycles render muscle cytoarchitecture susceptible to remodelling. Quantitative morphometry was introduced in living cells using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
