Article

Rab5 and Alsin regulate stress-activated cytoprotective signaling on mitochondria

2017-10-09

Abstract excerpt

Mitochondrial stress response is essential for cell survival, and damaged mitochondria are a hallmark of neurodegenerative diseases. It is thus fundamental to understand how mitochondria relay information within the cell. Here, by investigating mitochondrial-endosome contact sites we made the surprising observation that the small GTPase Rab5 translocates from early endosomes to the outer mitochondrial membrane upo...

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Literature Corpus work: 5c4929a6-0088-584d-9932-2e931c12d0cd
DOI: 10.1101/200428

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