Article

Reliable detection of genetic alterations in cyst fluid DNA for the diagnosis of brain tumors

2023-11-14

Abstract excerpt

<h4>Purpose: </h4> Liquid biopsy of cyst fluid in brain tumors has not been extensively studied to date. The present study was performed to see whether diagnostic genetic alterations found in brain tumor tissue DNA could also be detected in cell-free DNA (cfDNA) of cyst fluid in cystic brain tumors. <h4>Methods: </h4> Cyst fluid was obtained from 17 patients undergoing surgery for a cystic brain tumor with confirm...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5bd7ed54-4342-5481-8a83-35faefa7755a
DOI: 10.21203/rs.3.rs-3589356/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Reliable detection of genetic alterations in cyst fluid DNA for the diagnosis of brain tumorsDOI 10.21203/rs.3.rs-3589356/v1Read

Reliable detection of genetic alterations in cyst fluid DNA for the diagnosis of brain tumors.Semantic proximity Read

Classification of Brain Tumors by Nanopore Sequencing of Cell-Free DNA from Cerebrospinal Fluid.Semantic proximity Read

Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patientsSemantic proximity Read

Detection of tumor-derived cell-free DNA in cerebrospinal fluid using a clinically validated targeted sequencing panel for pediatric brain tumors.Semantic proximity Read

Optimization of a Protocol for Isolating Cell-free DNA From Cerebrospinal Fluid.Semantic proximity Read

Simultaneous Ultra-Sensitive Detection of Structural and Single Nucleotide Variants Using Multiplex Droplet Digital PCR in Liquid Biopsies from Children with MedulloblastomaSemantic proximity Read

Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method.Semantic proximity Read

Liquid Biopsy of Cerebrospinal Fluid Enables Selective Profiling of Glioma Molecular Subtypes at First Clinical Presentation.Semantic proximity Read

Cell Free DNA Extracted From Csf for Molecular Diagnosis of Pediatric Embryonal Brain TumorsSemantic proximity Read

TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomasSemantic proximity Read

Cerebrospinal Fluid from Cytology Supernatant as a Liquid Biopsy Specimen for Diagnosis and Surveillance for Pediatric Primary Central Nervous System TumorsSemantic proximity Read

A pilot study on the use of cerebrospinal fluid cell-free DNA in intramedullary spinal ependymoma.Semantic proximity Read