Article
Classification of Brain Tumors by Nanopore Sequencing of Cell-Free DNA from Cerebrospinal Fluid.
Clinical chemistry - 4 Jan 2024
Afflerbach Ann-Kristin, Rohrandt Christian, Brändl Björn, Sönksen Marthe, Hench Jürgen, Frank Stephan, Börnigen Daniela, Alawi Malik, Mynarek Martin, Winkler Beate, Ricklefs Franz, Synowitz Michael, Dührsen Lasse, Rutkowski Stefan, Wefers Annika K, Müller Franz-Josef, Schoof Melanie, Schüller Ulrich
Abstract excerpt
BACKGROUND: Molecular brain tumor diagnosis is usually dependent on tissue biopsies or resections. This can pose several risks associated with anesthesia or neurosurgery, especially for lesions in the brain stem or other difficult-to-reach anatomical sites. Apart from initial diagnosis, tumor progression, recurrence, or the acquisition of novel genetic alterations can only be proven by re-biopsies. METHODS: We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.