Article
Detection of H3F3A K27M or BRAF V600E in liquid biopsies of brain tumor patients as diagnostic and monitoring biomarker: impact of tumor localization and sampling method.
Acta neuropathologica - 3 Jan 2025
Madlener Sibylle, Stepien Natalia, Senfter Daniel, Mayr Lisa, Laemmerer Anna, Hedrich Cora, Baumgartner Alicia, Lötsch-Gojo Daniela, Sterba Jaroslav, Pokorna Petra, Kiesel Barbara, Widhalm Georg, Eckert Franziska, Preusser Matthias, Rössler Karl, Azizi Amedeo, Peyrl Andreas, Czech Thomas, Haberler Christine, Slavc Irene, Kasprian Gregor, Dorfer Christian, Furtner Julia, Gojo Johannes
Abstract excerpt
Gliomas are the most common brain tumor type in children and adolescents. To date, diagnosis and therapy monitoring for these tumors rely on magnetic resonance imaging (MRI) and histopathological as well as molecular analyses of tumor tissue. Recently, liquid biopsies (LB) have emerged as promising tool for diagnosis and longitudinal tumor assessment potentially allowing for a more precise therapeutic management....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.