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Droplet digital PCR-based detection of circulating tumor DNA from pediatric high grade and diffuse midline glioma patients

1 Jan 2021

Abstract excerpt

Abstract Background The use of liquid biopsy is of potential high importance for children with high grade (HGG) and diffuse midline gliomas (DMG), particularly where surgical procedures are limited, and invasive biopsy sampling not without risk. To date, however, the evidence that detection of cell-free DNA (cfDNA) or circulating tumor DNA (ctDNA) could provide useful information for these patients has been...

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PMID: 34169282
DOI: 10.1093/noajnl/vdab013

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