Article

TERT promoter mutation analysis for blood-based diagnosis and monitoring of gliomas

2020-09-04

Abstract excerpt

Liquid biopsy offers a minimally invasive tool to diagnose and monitor the heterogeneous molecular landscape of tumors over time and therapy. Gliomas have been challenging to sample with blood-based liquid biopsy due to low levels of circulating tumor-derived nucleic acid, and prior efforts have shown specific point mutations in less than 5% of glioma patients. Detection of TERT promoter mutations (C228T, C250T) i...

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Literature Corpus work: 116d7b3c-773c-5890-859b-370d7a54e6f3
DOI: 10.1101/2020.09.03.20135236

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