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Article

Reliable detection of genetic alterations in cyst fluid DNA for the diagnosis of brain tumors.

Journal of neuro-oncology - 1 Jan 2024

On Jotaro, Natsumeda Manabu, Takahashi Haruhiko, Koyama Akihide, Shibuma Satoshi, Shibata Nao, Watanabe Jun, Saito Shoji, Kanemaru Yu, Tsukamoto Yoshihiro, Okada Masayasu, Ogura Ryosuke, Eda Takeyoshi, Tada Mari, Shimizu Hiroshi, Adachi Jun-Ichi, Mishima Kazuhiko, Nishikawa Ryo, Kakita Akiyoshi, Oishi Makoto

Abstract excerpt

PURPOSE: Liquid biopsy of cyst fluid in brain tumors has not been extensively studied to date. The present study was performed to see whether diagnostic genetic alterations found in brain tumor tissue DNA could also be detected in cell-free DNA (cfDNA) of cyst fluid in cystic brain tumors. METHODS: Cyst fluid was obtained from 22 patients undergoing surgery for a cystic brain tumor with confirmed genetic...

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PMID: 38227143
DOI: 10.1007/s11060-023-04555-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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