Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A single-cell regulatory map of postnatal lung alveologenesis in humans and mice

1 Mar 2022

Abstract excerpt

Ex-utero regulation of the lungs’ responses to breathing air and continued alveolar development shape adult respiratory health. Applying single-cell transposome hypersensitive site sequencing (scTHS-seq) to over 80,000 cells, we assembled the first regulatory atlas of postnatal human and mouse lung alveolar development. We defined regulatory modules and elucidated new mechanistic insights directing alveolar...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital Diaphragmatic Hernia Studies
Share to Epigenetics and DNA Methylation
Share to Neonatal Respiratory Health Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35434692
DOI: 10.1016/j.xgen.2022.100108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A single-cell regulatory map of postnatal lung alveologenesis in humans and micePMID 35434692Read ↗

Chromatin and gene-regulatory dynamics of human pulmogenesis by single cell multiomic sequencingSemantic proximity Read ↗

FGF10 and Human Lung Disease Across the Life SpectrumSemantic proximity Read ↗

Clinical Interventions and Inflammatory Signaling Shape the Transcriptional and Cellular Architecture of the Early Postnatal LungSemantic proximity Read ↗

Single-cell RNA sequencing reveals the developmental program underlying proximal–distal patterning of the human lung at the embryonic stageSemantic proximity Read ↗

Multiplexed single-cell transcriptomic analysis of normal and impaired lung development in the mouseSemantic proximity Read ↗

Definition and Signatures of Lung Fibroblast Populations in Development and Fibrosis in Mice and MenSemantic proximity Read ↗

Single cell transcriptomic analysis of murine lung development on hyperoxia-induced damage.Semantic proximity Read ↗

Single cell transcriptomic profiling identifies molecular phenotypes of newborn human lung cellsSemantic proximity Read ↗

An integrated single-cell atlas of human lung across the lifespanSemantic proximity Read ↗

Translational mapping of spatially resolved transcriptomes in human and mouse pulmonary fibrosisSemantic proximity Read ↗

Developmental origins of cell heterogeneity in the human lungSemantic proximity Read ↗

Mapping spatially resolved transcriptomes in human and mouse pulmonary fibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.