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Species-specific basal fluidization shapes early forebrain development

2025-10-07

Abstract excerpt

The human forebrain exhibits an expanded surface area compared with other great apes. Despite progress in dissecting species-specific gene expression programs and cell lineages, the tissue-level physical mechanisms underlying human-specific neurodevelopment remain unclear. Here, by quantifying tissue dynamics and mechanics using oil microdroplets in cerebral organoids from humans, gorillas, chimpanzees, and mice,...

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Literature Corpus work
5baf7968-5cc2-5d92-8208-ce2d60695e41
DOI
10.1101/2025.10.07.680907
Open publication

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Species-specific basal fluidization shapes early forebrain developmentDOI 10.1101/2025.10.07.680907
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