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Article

Organoids reveal niche-specific mechanotransduction-guided human cortical patterning and cell fate acquisition

2026-07-16

Abstract excerpt

<h4>SUMMARY</h4> The highly dynamic mechanical environment of the developing cerebral cortex has the potential to encode information vital for neuronal differentiation. Changes in local biophysical properties have been implicated in processes ranging from the maintenance of neural progenitors to long-range axon guidance. However, whether cortical mechanics influence cellular organisation and specification during...

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Literature Corpus work
50b966b4-e8ac-5f94-8b86-b97a0e06daab
DOI
10.64898/2026.07.15.736390
Open publication

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Organoids reveal niche-specific mechanotransduction-guided human cortical patterning and cell fate acquisitionDOI 10.64898/2026.07.15.736390
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