Article
Synthetic lumen rounding directs neural progenitor division mode
2026-04-01
Abstract excerpt
Although function often follows form, the causal role of tissue geometry is difficult to disentangle in complex embryonic development. Brain organoids generated using diverse protocols and species display striking morphological variability, particularly in lumen shape; however, whether and how lumen geometry influences neural development remains unclear. Here, we manipulate lumen sphericity in human cerebral organ...
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Identifiers and source
- Literature Corpus work
- dd96511b-5ec6-5b4c-9617-1510d63ba7ba
- DOI
- 10.64898/2026.03.30.715222