Article
Neurodegenerative disorders: insights from the nematode Caenorhabditis elegans.
Neurobiology of disease - 1 Oct 2010
Dimitriadi Maria, Hart Anne C
Abstract excerpt
Neurodegenerative diseases impose a burden on society, yet for the most part, the mechanisms underlying neuronal dysfunction and death in these disorders remain unclear despite the identification of relevant disease genes. Given the molecular conservation in neuronal signaling pathways across vertebrate and invertebrate species, many researchers have turned to the nematode Caenorhabditis elegans to identify the...
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