Article

Linkage Analysis in Caribbean Hispanic Families with Puerto Rican Ancestry Idenitfies an Alzheimer Disease Locus on chromosome 9

2020-03-11

Abstract excerpt

<h4>Background</h4> The ancestral genetic heterogeneity (admixture) of Caribbean Hispanics makes studies of this population critical to the discovery of ancestry-specific genetic factors in Alzheimer disease. In this study, we performed whole genome sequencing in multiplex Caribbean Hispanic Puerto Rican families to identify rare causal variants influencing Alzheimer disease through linkage and segregation-based...

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Literature Corpus work: 5b91cba7-eabb-511b-a7bb-0299c7d4ccf4
DOI: 10.1101/2020.03.10.986083

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