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Article

Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease.

Archives of neurology - 1 Nov 2006

Lee Joseph H, Cheng Rong, Santana Vincent, Williamson Jennifer, Lantigua Rafael, Medrano Martin, Arriaga Alex, Stern Yaakov, Tycko Benjamin, Rogaeva Ekaterina, Wakutani Yosuke, Kawarai Toshitaka, St George-Hyslop Peter, Mayeux Richard

Abstract excerpt

OBJECTIVES: To identify novel candidate regions for late-onset Alzheimer disease (LOAD) and to confirm linkage in previously identified chromosomal regions. DESIGN: Family-based linkage analysis. SETTING: Probands with familial LOAD identified in clinics in the Dominican Republic, Puerto Rico, and the United States. Patients We conducted a genome scan in 1161 members primarily clinically diagnosed as having LOAD;...

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Identifiers

PMID: 17101828
DOI: 10.1001/archneur.63.11.1591

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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